That Little Itch

Learners that Leak Little Information

We study learning algorithms that are restricted to using a small amount of information from their input sample. We introduce a category of learning algorithms we term d-bit information learners, which are algorithms whose output conveys at most d bits of information of their input. A central theme in this work is that such algorithms generalize. We focus on the learning capacity of these algor...

That little matter of consciousness.

Little Things that Count in Transcriptional Regulation

Although the NF-kappaB transcription factor tolerates significant sequence variations in its DNA binding site, NF-kappaB sites show remarkable evolutionary stability. In this issue of Cell, demonstrate that a single nucleotide change in an NF-kappaB binding site changes the dependence of the promoter on a specific coactivator without affecting NF-kappaB binding. These data suggest that binding ...

It's the little things that count.

Join us as we learn and play with the little things that count! In this full day workshop, we will be working with Joe’s gadgets and cover exercises on the original pedi-pole. We will work the magic circle, toe corrector, 2x4, foot corrector, breath-aciser, sand bag, magic circle, neck stretcher, and the baby arm chair. How can they be used to gain the greatest benefit? How do they fit with the...

The little R cell that could.

Drosophila eye development provides an excellent model system to study the role of inter-cellular signaling in the specification of unique cell fates. Behavioral screens by Benzer and his colleagues led to the identification of a gene, Sevenless, a receptor tyrosine kinase (RTK) receptor, required for the specification of the UV sensitive R7 cell. Genetic analysis further showed that the Ras/Ra...